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au:"Morel, Carlos"

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Relevance of national, regional and global virome projects on pandemics prediction, prevention, and control: a social network analysis of GVP-citing articles
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Fonseca, Bruna de Paula

; Morel, Carlos Medicis

Memórias do Instituto Oswaldo Cruz

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2023, Volume 118 elocation e230116

Abstract: En | Text: En | PDF: En

BACKGROUND The Global Virome Project (GVP) was proposed in 2018 as an evolution of the USAID PREDICT project and was presented as a “collaborative scientific initiative to discover zoonotic viral threats and stop future pandemics”. The immediate response was mixed, with public health and scientific communities representatives showing skepticism, if not direct opposition. OBJECTIVES The economic, social, and health consequences of the coronavirus disease 2019 (COVID-19) pandemic demonstrated how unprepared the world was in the face of new pandemics. This paper analyses the impact of the GVP on the scientific and public health communities. METHODS Published scientific articles that cited the two 2018 seminal publications proposing the project were analysed using social network analysis methods. FINDINGS Encompassing the periods before and after the onset of the Covid-19 pandemic, the results indicate that (i) the concepts of the GVP have received more support than opposition in the scientific literature; (ii) its foundations should be updated to address the specific criticisms. MAIN CONCLUSIONS Shifting focus to national virome projects can provide tangible, regional benefits that can positively contribute towards a consensus on achieving a high level of preparedness for the ever-present possibility of the following global viral pandemic.

https://doi.org/10.1590/0074-02760230116

Significance of a neglected tropical disease: lessons from a paradigmatic case of ‘success in translation’
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Morel, Carlos M

Memórias do Instituto Oswaldo Cruz

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2022, Volume 117 elocation e200277

Abstract: En | Text: En | PDF: En

In a previous publication, I stressed the fundamental importance of research for improving health using as an example the control of Chagas disease in the Americas.(1) For that purpose, I analysed the major scientific breakthroughs and public health events from the 1909 discovery of Chagas disease and its causative pathogen, Trypanosoma cruzi, by Carlos Chagas,(2) through the successful control of its transmission by insect vectors in large regions of the Southern Cone countries in the 90s.(3) In the twenty years since that publication, Brazil and Latin American countries had to cope with a number of serious public health threats, old and new: (i) recrudescence of well-known diseases, such as dengue and yellow fever; (ii) emergence of viral diseases that had been restricted to other continents (Zika, Chikungunya); (iii) new epidemics (H1N1) or (iv) pandemics (COVID-19). Are there still some lessons from that success story against a neglected disease of the 90s that would be relevant today in the context of these recent challenges?

https://doi.org/10.1590/0074-02760200277

Why do we still have not a vaccine against Chagas disease? disease
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Camargo, Erney Plessmann

; Gazzinelli, Ricardo Tostes

; Morel, Carlos Médicis

; Precioso, Alexander Roberto

Memórias do Instituto Oswaldo Cruz

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2022, Volume 117 elocation e200314

Abstract: En | Text: En | PDF: En

This review does not intend to convey detailed experimental or bibliographic data. Instead, it expresses the informal authors’ personal views on topics that range from basic research on antigens and experimental models for Trypanosoma cruzi infection to vaccine prospects and vaccine production. The review also includes general aspects of Chagas’ disease control and international and national policies on the subject. The authors contributed equally to the paper. data Instead production Chagas subject paper

https://doi.org/10.1590/0074-02760200314

Política de Ciência, Tecnologia e Inovação em Saúde (CT&I/S): uma atualização para debate
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Guimarães, Reinaldo

; Morel, Carlos Medicis

; Aragão, Érika

; Paranhos, Julia

; Palácios, Marisa

; Goldbaum, Moisés

; Gadelha, Paulo

; Kropf, Simone

Ciência & Saúde Coletiva

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dec 2021, Volume 26 N. 12 Pages 6105 - 6116

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo O texto contém uma proposta atualizada de política de Ciência, Tecnologia e Inovação em Saúde no Brasil e a pertinência da atualização decorre do desastre nas atividades nesse terreno verificadas no país desde o início do atual governo federal em 2019, bem como dos desafios colocados pela emergência da pandemia COVID-19 desde 2020. Ele está organizado em cinco seções, a saber: Pesquisa em Saúde; Inovação Produtiva; Avaliação e Incorporação de Tecnologias em Saúde; Propriedade Intelectual em Saúde; Novos desafios colocados pela Pandemia. Os autores fazem parte do Comitê de Assessoramento em Ciência, Tecnologia e Inovação da Abrasco.

Abstract The text presents an updated proposal for a Health Science, Technology and Innovation Policy in Brazil, following the huge political turmoil in the country since 2019 and the COVID-19 pandemic since 2020. The proposal is presented in five sections: Scientific Research; Productive Innovation; Health Technology Assessment and Incorporation; Intellectual Property in Health; New challenges posed by the Pandemic. The authors take part in the Advisory Committee in Science, Technology and Innovation of the Brazilian Association of Collective Health.

https://doi.org/10.1590/1413-812320212612.18632021 1 downloads

Política de Ciência, Tecnologia e Inovação em Saúde (CT&I/S): uma atualização para debate
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Guimarães, Reinaldo

; Morel, Carlos Medicis

; Aragão, Érika

; Paranhos, Julia

; Palácios, Marisa

; Goldbaum, Moisés

; Gadelha, Paulo

; Kropf, Simone

Ciência & Saúde Coletiva

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dec 2021, Volume 26 N. 12 Pages 6105 - 6116

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/1413-812320212612.18632021

La ilegalidad como orden. Hegemonía y política migratoria en la República Dominicana
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Muñiz, Anselmo

; Morel, Carlos

Si Somos Americanos

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dec 2019, Volume 19 N. 2 Pages 27 - 48

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract: Since its inception, Dominican immigration policy with respect to Haiti has consisted in a Janus-faced strategy. On the one hand, an increasingly repressive and discriminatory legal order that is prejudiced against Haitian immigrants and their descendents has been established. On the other, extra-institutional exceptions are routinely generated in terms of regulations in order to create an uprooted and forsaken population with a precarious political and legal status. This strategy is a concrete aspect of a political hegemony built on a racist and conservative narrative about citizenship and identity in the Dominican Republic. In order to confront this strategy and redefine Dominican democracy in terms of pluralism, it is necessary to reconfigure the citizenry as the subject of democracy. If we define democracy as the constitution of citizenship following Balibar, or rather as inclusion in a political community of peers, we can expand the horizon of the political struggles of denationalized Dominicans and migrant workers in the country.

Resumen: Desde sus orígenes, la política migratoria dominicana frente a Haití ha estado marcada por una estrategia de doble cara: de un lado, se establece un orden cada vez más represivo y discriminatorio en perjuicio de los trabajadores migrantes haitianos y los dominicanos descendientes de estos trabajadores. Del otro, se generan excepciones extrainstitucionales a las reglas con el objetivo de generar una población desarraigada y desamparada, con un precario estatus político y legal en el país. Esta estrategia constituye un aspecto concreto de una hegemonía política que se sostiene sobre un relato conservador y racista acerca de la ciudadanía y la identidad en la República Dominicana. Para enfrentar esta estrategia y redefinir la democracia dominicana en términos pluralistas, es necesario reconfigurar la ciudadanía como sujeto de la democracia. Entender la democracia, siguiendo a Balibar, como constitución de la ciudadanía, vale decir, de autoinclusión en una comunidad política de pares, permite ampliar el horizonte de las luchas de dominicanos desnacionalizados y de trabajadores migrantes en el país.

1424 downloads

Brazilian Response to Global End TB Strategy : The National Tuberculosis Research Agenda
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Kritski, Afranio

; Barreira, Draurio

; Junqueira-Kipnis, Ana Paula

; Moraes, Milton Ozorio

; Campos, Maria Martha

; Degrave, Wim Mauritz

; Miranda, Silvana Spindola

; Krieger, Marco Aurelio

; Chimara, Erica

; Morel, Carlos

; Dalcolmo, Margareth Pretti

; Maciel, Ethel Leonor Noia

; Evangelista, Maria do Socorro Nantua

; Villa, Teresa Scatena

; Sanchez, Mauro

; Costa, Fernanda Dockhorn

; Queiroz, Inacio

; Oliveira, Martha Maria

; Souza Junior, Ruy

; Silva, Jose Roberto Lapa e

; Ruffino-Netto, Antonio

Revista da Sociedade Brasileira de Medicina Tropical

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feb 2016, Volume 49 N. 1 Pages 135 - 145

Abstract: En | Text: En | PDF: En

https://doi.org/10.1590/0037-8682-0330-2015 3881 downloads

Development, health, and international policy: the research and innovation dimension
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Buss, Paulo Marchiori

; Chamas, Claudia

; Faid, Miriam

; Morel, Carlos

Cadernos de Saúde Pública

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2016, Volume 32 Suppl. 2 elocation e00046815

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

Resumo: O objetivo central deste texto é discutir desenvolvimento e saúde sob a ótica da influência da governança da saúde global, utilizando como traçador a dimensão das políticas de pesquisa, desenvolvimento e inovação em saúde, que se referem, de um lado, a insumos importantes para o sistema de saúde - como fármacos e medicamentos, vacinas, reativos para diagnóstico e equipamentos e, de outro, a conceitos e práticas inovadoras para o aperfeiçoamento dos sistemas de saúde e da saúde pública. Examina os dois principais macroprocessos que influenciam o desenvolvimento e a saúde: a Agenda do Desenvolvimento para o pós-2015 e o processo sobre pesquisa e desenvolvimento, propriedade intelectual e acesso a insumos em saúde em curso na Organização Mundial da Saúde. Conclui que muito há que ser feito para que a referida Agenda possa representar um pacto político internacional coerente e viável, e que os dois macroprocessos relacionados com a inovação em saúde precisam ser agilizados, mas para isto torna-se necessária a democratização da participação dos maiores interessados - os pacientes e, de modo geral, a população dos países mais pobres - pois só desta maneira será superada a "soma zero" em que se encontra o embate entre os representantes de Estados-membros nos debates atuais.

Abstract: This text main objective is to discuss development and health from the perspective of the influence of global health governance, using as the tracer the dimension of research, development, and innovation policies in health, which relate to both important inputs for the health system, like drugs and medicines, vaccines, diagnostic reagents, and equipment, and innovative concepts and practices for the improvement of health systems and public health. The authors examine the two main macro-processes that influence development and health: the post-2015 Development Agenda and the process under way in the World Health Organization concerning research and development, intellectual property, and access to health inputs. The article concludes, first, that much remains to be done for the Agenda to truly represent a coherent and viable international political pact, and that the two macro-processes related to innovation in health need to be streamlined. But this requires democratization of participation by the main stakeholders - patients and the general population of the poorest countries - since this is the only way to overcome a "zero sum" result in the clash in the current debates among member State representatives.

Resumen: El objetivo central de este texto es discutir el desarrollo y la salud, desde la óptica de la influencia de la gobernanza de la salud global, utilizando como eje vertebrador la dimensión de las políticas de investigación, desarrollo e innovación en salud, que se refieren, por un lado, a insumos importantes para el sistema de salud -como fármacos y medicamentos, vacunas, reactivos para diagnóstico y equipamientos y, por otro, a conceptos y prácticas innovadoras, para el perfeccionamiento de los sistemas de salud y de la salud pública. Se examinan los dos principales macroprocesos que influencian el desarrollo y la salud: la Agenda del Desarrollo para el pos-2015 y el proceso sobre pesquisa y desarrollo, propiedad intelectual y acceso a insumos en salud, en curso dentro de la Organización Mundial de la Salud. Se concluye que se deben realizar muchos esfuerzos para que la referida agenda pueda representar un pacto político internacional coherente y viable, asimismo, los dos macroprocesos relacionados con la innovación en salud necesitan agilizarse, pero para esto es necesaria la democratización de la participación de los mayores interesados: los pacientes y, de manera general, la población de los países más pobres, pues sólo de esta forma será superada la "suma cero" donde se encuentra el embate entre los representantes de estados miembros en los debates actuales.

https://doi.org/10.1590/0103-311X00046815 460 downloads

Development, health, and international policy: the research and innovation dimension
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Buss, Paulo Marchiori

; Chamas, Claudia

; Faid, Miriam

; Morel, Carlos

Cadernos de Saúde Pública

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2016, Volume 32 Suppl. 2 elocation e00046815

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

https://doi.org/10.1590/0103-311X00046815 5163 downloads

10.

Debate on the paper by Guimarães
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Morel, Carlos Medicis

Cadernos de Saúde Pública

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aug 2014, Volume 30 N. 8 Pages 1598 - 1598

Abstract: En | Text: En | PDF: En

https://doi.org/10.1590/0102-311XCO010814 729 downloads

11.

Debate on the paper by Guimarães
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Morel, Carlos Medicis

Cadernos de Saúde Pública

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aug 2014, Volume 30 N. 8 Pages 1598 - 1598

Abstract: En | Text: En | PDF: En

https://doi.org/10.1590/0102-311XCO010814 357 downloads

12.

Proposta conceitual de telessaúde no modelo da pesquisa translacional
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Silva, Angélica Baptista

; Morel, Carlos Médicis

; Moraes, Ilara Hämmerli Sozzi de

Revista de Saúde Pública

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apr 2014, Volume 48 N. 2 Pages 347 - 356

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

OBJETIVO Rever relação conceitual entre telessaúde e pesquisa translacional. MÉTODOS Realizou-se busca bibliográfica sobre telessaúde nas bases Scopus, Cochrane BVS, Lilacs e Medline com a finalidade de encontrar experiências de telessaúde conjugadas com a discussão da pesquisa translacional em saúde. A busca recuperou oito estudos, que basearam a análise dos modelos das cinco etapas da pesquisa translacional com os múltiplos fluxos de política pública no contexto brasileiro da telessaúde. Esses modelos foram aplicados às atividades de telessaúde da Rede de Bancos de Leite Humano, na Rede Universitária de Telemedicina. RESULTADOS O ciclo da pesquisa translacional do leite humano coletado, armazenado e distribuído apresentou iniciativas de telessaúde integradas, tais como videoconferências, softwares e portais de síntese do conhecimento, compondo elementos de um ecossistema de informação, mediado por tecnologias da informação e comunicação no sistema de saúde. CONCLUSÕES A telessaúde deve ser compreendida como conjunto de atividades em rede mediadas por computação e que promovem a translação do conhecimento entre pesquisa e serviços de saúde.

OBJECTIVE To review the conceptual relationship between telehealth and translational research. METHODS Bibliographical search on telehealth was conducted in the Scopus, Cochrane BVS, LILACS and MEDLINE databases to find experiences of telehealth in conjunction with discussion of translational research in health. The search retrieved eight studies based on analysis of models of the five stages of translational research and the multiple strands of public health policy in the context of telehealth in Brazil. The models were applied to telehealth activities concerning the Network of Human Milk Banks, in the Telemedicine University Network. RESULTS The translational research cycle of human milk collected, stored and distributed presents several integrated telehealth initiatives, such as video conferencing, and software and portals for synthesizing knowledge, composing elements of an information ecosystem, mediated by information and communication technologies in the health system. CONCLUSIONS Telehealth should be composed of a set of activities in a computer mediated network promoting the translation of knowledge between research and health services.

https://doi.org/10.1590/S0034-8910.2014048004923 4199 downloads

13.

Proposta conceitual de telessaúde no modelo da pesquisa translacional
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Silva, Angélica Baptista

; Morel, Carlos Médicis

; Moraes, Ilara Hämmerli Sozzi de

Revista de Saúde Pública

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apr 2014, Volume 48 N. 2 Pages 347 - 356

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/S0034-8910.2014048004923 1927 downloads

14.

Políticas oficiales y patrimonialización en el carnaval porteño
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Morel, Carlos Hernán

Runa

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dec 2008, Volume 29 Pages 121 - 146

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

In this work we seek to do a critical analysis around the process of inheritance of carnival activities in the environment of Buenos Aires city. We will look at how the new legislation for the porteño carnival, passed and implemented recently, has contributed in modifying the relationships and in the internal configuration in this ambience of cultural production. This implies the emergence of new complementary situations, negotiation and conflict among the different agents involved in the celebrations of the porteño carnival. First of all, we are interested in describing and analyzing the implementation process of formal devices, whose main objective is to regulate the activities of carnival groups. We will later examine how these official regulations establish a frame and meaningful categorizations over the practices and representations of the carnival groups, as well as which difficulties are arise at the moment of its cultural management.

En este trabajo nos proponemos realizar un análisis crítico en torno al proceso de patrimonialización de las actividades carnavalescas en el ámbito de la Ciudad de Buenos Aires. Veremos cómo, a partir de la sanción y puesta en marcha de una nueva legislación para el carnaval porteño, se modifican las relaciones y la configuración interna de este espacio de producción cultural. Ello implicará la emergencia de nuevas situaciones de complementariedad, negociación y conflicto entre los distintos agentes involucrados en los festejos del carnaval porteño. Principalmente nos interesa describir y analizar el proceso de implementación de dispositivos formales, cuyo objetivo es regular las actividades de las agrupaciones de carnaval. Examinaremos cómo, a partir de estas normativas oficiales, se establecen demarcaciones y categorizaciones significativas sobre las prácticas y representaciones de las agrupaciones de carnaval, como así también las dificultades que surgen al momento de su gestión cultural.

420 downloads Cited 1 time in SciELO

15.

Inovação em saúde e doenças negligenciadas
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Morel, Carlos M.

Cadernos de Saúde Pública

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aug 2006, Volume 22 N. 8 Pages 1522 - 1523

Abstract: Pt | Text: Pt | PDF: Pt

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